Brazil made light work of their last-16 meeting with South Korea to book their spot in the quarter-finals.
Croatia squeezed through on penalties against Japan and do have previous in forcing their way into the deepest stages of tournaments.
The World Cup quarter-final is scheduled for a 3pm GMT kick-off time on Friday December 9, 2022. Education City Stadium in Al-Rayyan will host.
Mateo Kovacic was substituted against Japan and is thought to be carrying an injury, while Luka Modric was also forced off.
For Brazil, Gabriel Jesus and Alex Telles are not available, though there are little other fresh injury problems, with Alex Sandro pushing for a return.
Brazil looked to have click, while Croatia rather limped into the last eight. Though they are a team to be feared, Brazil will surely have too much. Brazil to win 2-0.